Alli Long Term Safety Unknown

Alli safety: Still largely unknown

If you're among those who can benefit from a weight-loss drug alli, you'll likely need to take it indefinitely. When you stop alli treatment, however, much or all of the lost weight generally returns. The dilemma with taking the drugs indefinitely is that the most common weight-loss drugs are so new that possible long-term effects are unknown.

Sibutramine can cause a small increase in blood pressure that, for some people, may warrant discontinuing the drug. This drug isn't recommended for people with uncontrolled high blood pressure, heart disease, irregular heartbeat or a history of stroke.

alli (Orlistat) decreases the absorption of certain fat-soluble vitamins — for example, vitamins A, D and E. If you're taking this drug, your doctor will recommend that you take a daily vitamin supplement to prevent potential nutrient deficiencies.